Mission Mill Museum interprets the history of the Thomas Kay Woolen Mill which produced wool products from 1889 to 1962 and represents one of Oregon's earliest and strongest industries. Mission Mill also interprets the history of Jason Lee's Methodist Mission to Oregon which settled in the Willamette Valley in 1834 before the major Oregon Trail migrations. The missionaries brought formal education, industry, and large scale agriculture and advocated for U.S. government in the Oregon country. The Museum preserves Mission houses; an Oregon Trail settler's house; a historic church; and the structures, equipment, and original water-powered turbine of the Thomas Kay Woolen Mill with related artifacts. The museum's two histories are shared with visitors through individual and group tours, interpretation, speakers, living history, children's programs, hands-on activities, and special events.

The museum offers exhibits, tours, workshops, educational programs, and recreational and educational events.

The 18th-century Sherwood-Jayne house is located in a bucolic setting with sheep grazing in the adjoining pasture. Hand-painted floral wall frescoes imitating expensive wallpaper decorate the east parlor. The property has retained its 19th-century agrarian context—hayfields, meadows, woodlot, and orchard.

The site offers tours and educational programs.

The Stabler-Leadbeater Apothecary Museum, one of the oldest pharmacies in the nation, exists today to promote a greater understanding of historic public health issues; inspire people with the values of Quaker founder, Edward Stabler; and engage the visitor in an appreciation of local and national history by sharing the story of this business and family's profound effect on the community in such diverse areas as education and the abolition of slavery.

The site offers exhibits.

The Redwood Library and Athenæum is the oldest lending library in America, and the oldest library building in continuous use in the country. Founded in 1747 by 46 proprietors upon the principle of "having nothing in view but the good of mankind," its mission continues over 250 years later.

The library offers tours, exhibits, and all standard library services (including recreational and educational events, though not focused specifically on history).

Situated on the banks of the Suwannee River, this center honors the memory of American composer Stephen Foster, who wrote "Old Folks at Home," the song that made the river famous. The museum features exhibits about Foster's most famous songs and his music can be heard emanating from the park's 97-bell carillon throughout the day. In Craft Square, visitors can watch demonstrations of quilting, blacksmithing, stained glass making, and other crafts.

The park offers exhibits, demonstrations, workshops and classes, and educational and recreational events.

The history of this National Landmark began in 1528 when Panfilo de Narvaez arrived in the area with 300 men; however, the first fort was not built until 1679. Andrew Jackson occupied the fort for a brief time in the early 1800s. The museum at the park displays pottery and tools unearthed near the original fort and explains the history of the San Marcos site.

The park offers exhibits and tours.

A young physician named John Gorrie moved to Apalachicola in the early 1800s when it was a prominent port of trade, commerce, and shipping in Florida. Gorrie served as postmaster, city treasurer, town councilman, and bank director. Concern for his yellow fever patients motivated Gorrie to invent a method for cooling their rooms. He became a pioneer in the field of air conditioning and refrigeration by inventing a machine that made ice, and received the first U.S. Patent for mechanical refrigeration in 1851. A replica of his ice-making machine is on display at the museum, as well as exhibits chronicling the colorful history of Apalachicola, which played an important role in Florida's economic development.

The park offers exhibits.