The Italianate structure known as the U. S. Grant Home was built in 1859–60 as a residence by Alexander J. Jackson of Galena. When Ulysses S. Grant returned to the city in 1865 as a Civil War hero, he was presented the house as part of the city's celebration. All of the rooms are decorated and furnished to represent the mid-1860s. Many of the furnishings belonged to the Grant family.

The site offers exhibits, tours, and occasional recreational and educational events.

The Lower Cape Fear Historical Society seeks to preserve and share the history of southeastern North Carolina. To this end, the society operates the Latimer House Museum. The 1852 Victorian Italianate Latimer House contains period rooms depicting local upper-class Victorian-era life. The grounds contain gardens with heirloom plants.

The society offers a fifth grade educational program, guided tours of the house, guided historical district walking tours, a summer camp, and archival access. Reservations are required for the educational program. Non-members are charged a fee for archival access.

The Limberlost State Historic Site interprets one of the homes of author, photographer, naturalist, and illustrator Gene Stratton-Porter (1863-1924). Topics covered include Stratton-Porter's life, her writings, and the swamp surrounding Limberlost. The Limberlost swamp stretches over 13,000 acres, and was known circa 1900 for its multitude of dangers—natural and human. The residence itself is an 1895 Queen Anne cabin. Today, the interior holds Victorian and Arts and Crafts period rooms. Stratton-Porter was the author of numerous popular novels and nature books, including Freckles and A Girl of the Limberlost.

The site offers period rooms, guided house tours, and hiking trails. Group tours, school tours, outreach programs, and educational materials for rental are all available with advance notice. The website offers a list of state educational standards relevant to the site.

The temple is the oldest continuously used Chinese temple in California. On display are art objects, pictures, mining tools, and weapons used in the 1854 Tong War. This Taoist temple is still a place of worship and a fascinating look into the role played by Chinese immigrants in early California history. The temple was built in 1874 as a replacement for another that had burned. Many of the historical objects have been restored and the structure itself stabilized.

The park offers exhibits, tours, and educational and recreational events.

The National Museum of Civil War Medicine presents the technological techniques and changes made in medicine between 1861 and 1865, as well as the stories of those involved with Civil War-era medicine—soldiers, medical practitioners, and their families. Topics include medical education, recruitment, camp life, evacuation of the wounded, field dressing stations and hospitals, embalming, and modern military medicine. Frederick, Maryland, site of the museum, was the location of forty Civil War skirmishes and battles. The museum has an additional location at the Pry House Field Hospital Museum on the Antietam National Battlefield. This site focuses on the development of first aid and emergency medicine during the 1862 Battle of Antietam, also known as the Battle of Sharpsburg.

The museum offers exhibits, 90-minute guided tours, question and answer sessions, hands-on activities, lectures, educational programs, and research assistance. Payment is required for research assistance.

On October 25, 1864, approximately 2,800 Union troops attacked and defeated about 8,000 Confederates along the banks of Mine Creek. This was one of the largest cavalry battles in the Civil War and was the only major battle fought in Kansas. The Union brigades were commanded by Colonels Frederick W. Benteen and John F. Philips. After this battle, Federal forces pursued and defeated additional Confederates in Missouri as they attempted to return to Arkansas, Indian Territory (Oklahoma), and eventually Texas. Visitors to the site can learn more about the soldiers and their stories as this dramatic story comes alive at the Mine Creek Battlefield.

The site offers exhibits, occasional living history events, tours, and occasional recreational and educational events.

The Thomas Edison House served as Thomas Edison's (1847-1931) residence between 1866 and 1868. Built circa 1850, the home now contains collections including cylinder and disc phonographs, Edison Business Phonographs, an Edison Kinetoscope, and early light bulbs. Thomas Edison is best known for his invention of the electric light bulb. However, while living at this site, his main interest was improving telegraph technology.

The house offers exhibits, period rooms, guided tours, 10 through 35-minute films, a learning module which encourages creation of student inventions, and hands-on telegraph demonstrations.

The Pioneer Living History Village is a 90-acre living history 1800s town. Structures are either period or reproductions based on historical research. Sights include an opera house in which Lilly Langtry (1853-1929), famed English actress and beauty, once sang; the childhood home of Henry Fountain Ashurst (1874-1962), one of the first Senators of Arizona; and a circa 1880 cabin which survived an Apache raid.

The museum offers period rooms, demonstrations, living history interpreters, and re-enactments. The museum is closed on rainy days.

When gold was found in Idaho in 1860, an Assay Office was set up to test the purity of the mined gold before it could be shipped. By 1870, the office was complete. Today it is a museum for Idaho's mining history.

The office currently cannot accommodate visitors. The Idaho Historic Society does however offer in-class educational programs on mining and other topics. Travelling trunks for grades 3-12 are available for lending. Outreach opportunities on variety of subjects are also available for grades 4-12.Videos, slide shows, and lesson plans are obtainable for educators.

The Museum tells the stories of 97 Orchard Street. Built on Manhattan's Lower East Side in 1863, this tenement apartment building was home to nearly 7,000 working class immigrants. They faced challenges people understand today: making a new life, working for a better future, starting a family with limited means. In recognizing the importance of this seemingly ordinary building, the Tenement Museum has reimagined the role that museums can play in modern lives.

The museum offers exhibits, tours, educational programs, and educational and recreational events.