The Foundation operates four historic house museums, including the 1858 Greek Revival style Earle-Napier-Kinnard House, the 1877 Italianate Villa East Terrace, the 1868 Greek Revival Style Fort House, and the 1866 McCulloch House. Fort House Museum displays exhibits from the Heritage Collection of textiles, garments, and accessories; and the other homes display seasonal vignettes from the collection. The Foundation itself is housed in the 1890s Queen-Anne-style Victorian Hoffman House.

The houses offer tours, exhibits, lectures, workshops, and other educational and recreational programs.

The Kaw Mission houses a museum that tells the story of the building that was home and school to thirty Kaw boys from 1851–1854. The Kaw lived in the Neosho Valley for less than thirty years when, despite an impassioned plea by Chief Allegawaho, the U.S. government removed the Kaw to Indian Territory (now Oklahoma). At the museum, visitors can learn more about Chief Allegawaho, the Kaw Indians, and others who lived in the area.

The site offers exhibits, a short film, and tours.

The Society operates the McLean County Museum of History, housed in the Old McLean County Courthouse. The Museum presents exhibits and programs that explore the history of Central Illinois and its people.

The museum offers exhibits, tours, workshops, and other educational and recreational programs.

The Roberson Museum and Science Center is a complex of educational institutions, including historic buildings and museum exhibits and facilities treating art, history, and science.

The museum offers exhibits, tours, film screenings, classes, and other educational and recreational events.

The Museum was built in 1876 as the First Universalist Church, and served as the Potsdam Public Library, with the Museum in the lower level, from 1940 until 1976. Today, it is dedicated to the collection, preservation, and interpretation of local history and the decorative arts. The Museum exhibits artifacts related to the Knowles Family of Potsdam and the history of Potsdam, as well as ceramic, pottery, and porcelain pieces drawn from the Burnap Collection.

The museum offers exhibits, research library access, and educational and recreational events.

The Mystic River Historical Society, founded in 1973, owns an ever-growing collection of Mystic-related historical books, maps, photographs, and other documents and artifacts contributed by the community. It houses these collections in the William A. Downes Archives Building, erected by the Society specifically to provide a safe environment for them. It maintains part-time archival and curatorial staff available to assist researchers and to continue the organization and cataloging of the collections. In addition to the Downes Building, the Society owns the 1839 Portersville Academy, purchased from the Town of Groton in 1975 and partially restored. This historical building serves as the Society's education and outreach space. A schoolroom of the 1840s has been recreated upstairs, and historical displays form a backdrop for educational activities downstairs.

The society offers exhibits, lectures, tours, research library access, and educational programs.

The Society's museum is housed in the 1773 home of Dr. William Henry Stoy, a local minister and prominent Revolutionary War doctor. Throughout the museum, visitors will find examples of Pennsylvania German craftsmanship in such items as furniture, quilting and weaving, fraktur, and redware. Exhibits include recreations of several early shops and offices and explorations of community industries such as blacksmithing, farming and milling, carpentry, weaving, printing, shoemaking, and mining.

The museum offers exhibits, tours, and research library access; the society offers educational and recreational programs.

Old Salem includes four museums—the Historic Town of Salem, the Museum of Early Southern Decorative Arts (MESDA), the Old Salem Children's Museum, and the Old Salem Toy Museum— which engage visitors in an educational historical experience about those who lived and worked in the early South.

The museums offer exhibits, tours, demonstrations, and other recreational and educational events (including living history events).

The Titan Missile Museum is the only publicly accessible Titan II missile site in the nation. Visitors can tour the underground missile site and see the 3-ton blast doors, the 8-foot-thick silo walls, and an actual Titan II missile in the launch duct. They can also visit the launch control center and experience a simulated launch.

The museum offers tours and educational and recreational programs.

Since 1830, the Society has connected people to the past by collecting, preserving, interpreting, and disseminating the state's history. A nonprofit membership organization, the IHS also publishes books and periodicals; sponsors teacher workshops; provides youth, adult, and family programming; provides support and assistance to local museums and historical groups; and maintains the nation's premier research library and archives on the history of Indiana and the Old Northwest. The society also maintains the Indiana History Center, where events and programs are held and exhibits housed.

The center offers exhibits, tours, lectures, film screenings, research library access, and educational and recreational programs.