The 7.4–acre Battle of Carthage Historic Site preserves the location of the Battle of Carthage, one of the earliest engagements in the Civil War, fought 5 July, 1861. The site includes a portion of the battleground, as well as the site of both the Union and Confederate camps. The battle itself, a Confederate victory, was led by Union Colonel Franz Sigel and Confederate Governor Claiborne Jackson. In this skirmish, Sigel attempted to prevent Jackson's men from banding together with other nearby Confederate troops.

The site offers an informational kiosk.

Harry Truman was born in a modest frame house in Lamar, Missouri. The home has been faithfully preserved so that modern visitors can explore the home exactly as it was during the first year of Harry Truman's life. The home has no electricity or running water, and is furnished in a manner typical of the late 1800s.

The home offers guided tours. The website offers a brief history and visitor information.

In 1804, Lewis and Clark reported the presence of many saltwater springs in the area that now comprises Howard, Cooper, and Saline counties. The largest of these salt springs was the Boone's Lick. The area around this spring was ideal for settlement and for many years "Boone's Lick Country" was a primary destination for pioneers moving west. Nathan and Daniel Morgan Boone, sons of famous frontiersman Daniel Boone, formed a partnership with James and Jesse Morrison in 1805 to produce salt. Brine water was poured into iron kettles and heated to boiling on a stone furnace. As the water evaporated, salt crystallized in the bottom of the kettle. The salt was shipped by keelboat on the Missouri River to St. Louis. Salt, which was indispensable at the time for preserving meat and tanning hides, was produced at the site until approximately 1833. Today, the 52-acre site features picnic facilities and a short trail that winds its way to the spring site, where wood remnants of the salt works and an iron kettle are still visible. Outdoor exhibits interpret this unique saltwater environment and center of frontier industry. Artifacts from the salt manufacturing industry were excavated at the site, and some are on display at the Arrow Rock State Historic Site visitor center in Arrow Rock.

The site offers exhibits and occasional recreational and educational events.

The Pommer-Gentner house, built in 1840, is a sterling example of high-style German neoclassicism and is furnished to reflect the earlier settlement period of the 1830s and 1840s. Behind the house, visitors will tour a period garden and a small half-timbered barn containing an exhibit of 19th-century tools. The Strehly house, built in stages from 1842 to 1869, has a traditional German vernacular front. It once contained a full-service printing company that produced a German-language newspaper. About 1857, Carl Strehly built a winery next to the house that today displays one of a few remaining carved wine casks in the Midwest. Grapevines, planted by the Strehlys in the 1850s, can still be seen running the length of the backyard. Deutschheim's varied collections of German Americana are represented by galleries of changing artifacts and photographs.

The site offers tours, exhibits, occasional recreational and educational events.

Missouri's first legislators met in the buildings of the First Missouri State Capitol State Historic Site to undertake the task of reorganizing Missouri's territorial government into a progressive state system. From June 4, 1821, to Oct. 1, 1826, heated debates of state's rights and slavery filled the rooms of the temporary Capitol. The second floor of two adjoining Federal-style brick buildings was divided and used as Senate and House chambers, an office for the governor, and a small committee room. The first floor of the Peck brothers' building housed a general store and Ruluff Peck's family residence. Chauncy Shepard operated a carpenter shop on the first floor of the adjoining building. For a nominal fee, visitors can take a guided tour through the actual restored and furnished rooms where Missouri state government was created and first practiced. The restored Peck brothers' general store and residence have been furnished as they might have looked in the early 1800s. Admission is free to the historic site's interpretive center, which offers two floors of exhibits and an orientation show.

The site offers a short film, exhibits, tours, and occasional recreational and educational events.

Sandy Creek Covered Bridge boasts the appearance of an old red barn. It was one of six bridges built in 1872 to allow passage from the Jefferson County seat of Hillsboro to St. Louis.

The site is open to the public, but unstaffed; however, interpretive programs for groups may be arranged.

Mastodon State Historic Site contains an important archaeological and paleontological site—the Kimmswick Bone Bed. Bones of mastodons and other now-extinct animals were first found here in the early 1800s. The area gained fame as one of the most extensive Pleistocene Ice Age deposits in the country and attracted scientific interest worldwide. Today, the 425-acre property preserves this National Register of Historic Places site and provides recreational opportunities. A museum tells the natural and cultural story of the oldest American Indian site one can visit in the state's park system. A full-size replica of a mastodon skeleton highlights the exhibits. A picnic area, several trails, and a special-use camping area offer chances to explore the land where the lives of Native Americans and mastodons once intertwined.

The site offers exhibits, a slideshow, tours, and educational programs.

Jewell Cemetery State Historic Site, Columbia, contains the grave of Missouri's 22nd governor (1875–1877), Charles Hardin, along with descendants of George Jewell. The most well-known member of the Jewell family buried in the cemetery, William Jewell, died while establishing a college in Liberty, MO, that bears his name.

The site is open to the public.

Website does not specify any interpretive services available at the site.

A renowned painter, sculptor, lecturer, and writer, Thomas Hart Benton had a gift for interpreting everyday life. One of his most noted murals, "A Social History of the State of Missouri," can be viewed in the House Lounge of the state Capitol. Virtually untouched since his death in 1975, the two-and-a-half story, late Victorian-style house that Benton called home was constructed of native, quarried limestone and contains simple furnishings in neutral tones that contrast Benton's vibrant paintings. Several of Benton's paintings and sculptures can be viewed in the house. Benton converted half of the carriage house into his art studio, which remains as he left it, with coffee cans full of paintbrushes, numerous paints, and a stretched canvas waiting to be transformed into another of his masterpieces.

The site offers tours.

A barn-red mill nestled among green trees beside blue waters rolling over a rock dam create the colorful setting of one of Missouri's most picturesque historic sites. Dillard Mill State Historic Site interprets one of Missouri's best-preserved, water-powered gristmills. Completed in 1908, Dillard Mill sits along Huzzah Creek and was the second mill built at that site. The first, Wisdom's Mill, built in the 1850s, was destroyed by fire in 1895. Innovations in the new, modernized mill included steel roller mills for grinding the wheat and a turbine to power the mill. For years, farmers brought their grain to the mill to be ground into flour and eventually livestock feed. The mill ceased operation in 1956. Today, most of the original machinery is still intact and operational. A turn of a wheel brings the machinery back to life during tours of the mill, which are given year-round.

The site offers tours.