Interactive exhibitions and resources address the Holocaust and related subjects. The site is composed of five sections: education, research, history, remembrance, and conscience.

"Education" introduces the subject of the Holocaust and provides extensive bibliographies. "Research" contains a survivor registry and an international directory of activities relating to Holocaust-era assets. Searchable catalogs pertaining to the Museum's collections and library are easy to navigate to find artworks, artifacts, documents, photographs, films, videos, oral histories, and music. "History" includes the Holocaust Learning Center, with images, essays, and documents on 75 subjects, such as anti-Semitism, refugees, pogroms, extermination camps, and resistance. "Committee on Conscience" contains information on current genocidal practices in Sudan.

This collection of more than 1,230 images depicts the enslavement of Africans, the Atlantic Slave Trade, and slave life in the New World. Images are arranged in 18 categories, including pre-Colonial Africa, capture of slaves, maps, slave ships, plantation scenes, physical punishment, music, free people of color, family life, religion, marketing, and emancipation.

Many of the images are from 17th- and 18th-century books and travel accounts, but some are taken from sketches within slave narratives, Harper's Weekly, and Monthly Magazine. Reference information and brief comments, often an excerpt from original captions, accompany each image. Although there is no interpretation or discussion of historical relevance, these images are valuable for learning about representations of slavery in American slave societies, especially in the Caribbean and Latin America.